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In a phase 2 trial, tesofensine at the 0.5 mg dose with diet induced a mean weight loss of 9.2% over 24 weeks, greater than diet and placebo, which produced 2.0%

The companys 2025 guidance is for a decline of nearly $3bn on 2024s revenues

Preference between them often comes down to whether a patient can tolerate weekly injections or strongly prefers a pill

Perhaps the most alarming aspect is the significant muscle loss many experience while on the GLP-1 RAs

The company hasn't submitted its weight loss pill, orforglipron, to the agency yet
