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Elashoff M, et al

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During the shortage, clinicians are also required to: Only prescribe GLP-1 RAs for their licensed indication Review the need for prescribing a GLP-1 RA agent and stop treatment if no longer required due to not achieving desired clinical effect as per NICE CG28 Avoid switching between brands of GLP-1 RAs, including between injectable and oral forms Where a higher dose preparation of GLP-1 RA is not available, do not substitute by doubling up a lower dose preparation Where GLP-1 RA therapy is not available, proactively identify patients established on the affected preparation and consider prioritising for review based on the criteria below

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Try to drink 8 to 10 (8-ounce) cups of liquids every day

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Diuretics Mechanism: Increase sodium and water excretion blood volume blood pressure Types & Examples: Thiazide: Hydrochlorothiazide, Chlorthalidone Loop: Furosemide, Bumetanide Potassium-sparing: Spironolactone, Amiloride Key Points: First-line for uncomplicated hypertension, especially thiazides 2

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