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Recently, the GLP-1R has been found in human colon cell culture models, and in the colonic epithelium [67]

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Cells producing and secreting enteroglucagon were originally identified by immunohistochemistry with glucagon antibodies and it was noted that the cells in the gut mucosa differed from islet -cells that produce glucagon (42)

Large cardiovascular trials and pooled analyses have not shown a statistically higher pancreatitis incidence than placebo beyond what is expected in diabetics (who inherently have some risk)

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