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Nonetheless, no significant increase in the risk of TOP was observed when the GLP1-RA group was compared with the overweight/obese reference group (HR, 1.79
doi: 10.3390/ijms23020739 22 LiQXGaoHGuoYXWangBYHuaRXGaoLet al
Over time, this chronic immune attack results in a gradual loss of functional thyroid tissue, with the clinical course typically progressing from an initial euthyroid state to subclinical hypothyroidism and, in a subset of patients, overt hypothyroidism requiring lifelong thyroid hormone replacement [13,14]
Mood and appetite are closely related (think of stressful eating or eating when we are sad, comfort food), and a benefit of GLP1-Ra is that they help control appetite and satiety, which allows patients to make better meal choices and become healthier
Those SCFAs, particularly butyrate and propionate, stimulate gut L-cells to release GLP-1 and PYY, two appetite-regulating hormones
