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One small study found no increased risk of major birth defects or miscarriage among women who took GLP-1 RAs during their first trimester

Research shows that Saxenda can help with steady weight loss, though it may not be as strong as some new options
Drummond RF, Seif KE, Reece EA
5,6,7 GLP-1 is a peptide produced by the cleavage of proglucagon, mainly synthesized in the intestinal mucosal L-cells, pancreatic islet -cells, and neurons in the nucleus of the solitary tract

Non-genetic predictors of BMI loss We examined non-genetic factors that were predictive of GLP1 medication efficacy, as measured by the percentage change in BMI from baseline (BMI % )
