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GLP-1 medications are changing how people think about weight loss and how they actually lose weight, driving changes in views about obesity care among health systems and providers and affecting the broader US economy. These drugs hold the potential to help address what continues to be an increasing obesity problem in the US. A 2024 []

GLP-1 receptor agonists including semaglutide must be stopped before pregnancy due to animal studies showing potential fetal harm

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Using a global dataset and propensity matching, they found significantly lower mortality rates, major cardiovascular events (MACEs), and adverse kidney outcomes (MAKEs) among GLP-1 RA users compared to non-users

It rewires how your brain interprets fullness signals, slows stomach emptying, and adjusts appetite-control hormones like peptide YY and cholecystokinin