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10.1016/j.brainres.2005.08.053 96 TakedaN.HasegawaS.MoritaM.MatsunagaT

As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)

Weight loss and improved metabolic control during treatment may restore ovulatory function, particularly in women with obesity-related reproductive dysfunction, increasing the likelihood of unintended pregnancies

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