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For instance, while medications like Lexapro and Zoloft work by increasing serotonin, GLP-1 RAs seem to influence mood through reward pathways and hormonal regulation

10.1016/j.ijsu.2021.105906 50 PalmerA

Based on rats studies, they also proposed the theory of the foregut exclusion hypothesis which suggests that delivery of nutrients to proximal small intestine leads to a release of a pro-diabetic factor, which is over secreted in diabetics [32]
