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Liraglutide ameliorates renal injury in streptozotocininduced diabetic rats by activating endothelial nitric oxide synthase activity via the downregulation of the nuclear factorkappaB pathway

Most GLP-1 users accidentally undereat protein by 40% or more because appetite suppression works so effectively, accelerating muscle loss that undermines long-term metabolic health and creating plateaus that feel like treatment failure

That means one of the most important messages for patients is this: Do not judge your health by the scale alone

doi: 10.1016/j.mce.2015.07.003

In contrast to previous studies, the incidence of bowel obstruction (including ileus, intussusception, volvulus, neurogenic bowel, megacolon, and other types of bowel obstruction) was not found to differ between SGLT-2 inhibitors and GLP-1RAs but tended to be nonsignificantly protective against these diagnoses (adjusted HR 0.83 [95% CI 0.69 to 1.01])