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Glucagon-like peptide-1 receptor agonists (RAs) are an important class of drugs with a well-established efficacy and safety profile in patients with type 2 diabetes mellitus

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Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1. Cell Metabolism , 27(4), 740756

5.3 Lean Mass and Body Composition Weight loss trials indicate that: 2040% of weight lost may include lean mass, depending on protein intake and physical activity. Lean mass loss itself does not cause micronutrient deficiency, but it may reflect: Reduced protein intake Reduced intake of iron- and zinc-rich foods Reduced intake of B vitamins Clinical oversight of protein intake is therefore a practical nutritional priority