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Contrave (naltrexone/bupropion) has demonstrated effectiveness for long-term weight loss when used in conjunction with a reduced-calorie diet and regular exercise
metabolic rate reductions during treatment are primarily attributable to weight loss itself rather than a specific drug effect
10.1523/JNEUROSCI.0226-14.2014 [DOI] [PMC free article] [PubMed] [Google Scholar] Thomas, M
Fatigue: Some people feel temporary tiredness as their body adjusts to a lower caloric intake
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