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[15] [16] When used with insulin or sulfonylureas, dose adjustments of these medications may be needed to reduce hypoglycaemia risk

injected GLP-1 analog, liraglutide (LIR), into mice

Its action on GIP and GLP-1 receptors enhances appetite control and metabolic function, suggesting higher efficacy compared to single GLP-1RAs

Treatment with GLP-1RA or SGLT2-I was defined as at least three dispensations of the medication

Por otro lado, los frmacos de accin prolongada, permiten un mayor control de la glucemia basal, como la exenatida de liberacin prolongada, liraglutida, dulaglutida, albiglutida y por ltimo semaglutida, aprobada recientemente por la FDA 56 .Adems, se ha demostrado que los GLP1-RA disminuyen el riesgo de eventos cardiovasculares al influir positivamente en factores de riesgo como obesidad, presin arterial y perfil lipdico 15