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122124 Patient education is critical to ensure awareness of biliary complications, emphasizing gradual weight loss, balanced diets, and regular physical activity to optimize bile composition and motility

Cost & Access The out-of-pocket cost of GLP-1 medications can be exceptionally steep

These data strongly suggest that GLP-1R agonists are beneficial to attenuate neuroinflammation-associated cognitive impairment and thereby improve cognition

Evidence for a direct mechanism is limited and will be more thoroughly examined in the mechanistic REMODEL trial (NCT04865770)

Cadet P (2007) A functionally coupled mu3-like opiate receptor/nitric oxide regulatory pathway