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The latest diabetic retinopathy preferred practice guidelines from the American Academy of Ophthalmology indicate that the rising use of GLP-1RAs may lead to quick glycemic control and severe hypoglycemia and has been reported to cause higher rates of retinopathy complications, especially in patients with early-stage DR (Lim et al., 2025)

That means that metformin actually makes your body more SENSITIVE to the insulin that is already in circulation and this is a good thing, we want this to happen

Research on this topic is still ongoing, however, and it may take time to determine the long-term effects of these drugs

understanding Wegovy requirements may help you navigate approval

In contrast, GLP-1 injectables, such as Ozempic, Wegovy, Zepbound, and Mounjaro, are prescription medications that help with weight loss in obesity and diabetes management