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Rates of hypoglycemia and GI intolerance were similar among the active-treatment groups, but body weight decreased in patients taking sitagliptin (0.4 kg) or placebo (0.8 kg) and increased in those taking rosiglitazone (+1.5 kg)

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This is a perfect example of nature-inspired biology

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The reasons behind the framework (muscle preservation, gallbladder protection, steady nutrient delivery) remain just as relevant at week 30 as they were at week 3