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Description
Most clinical pathways look like this: Diagnose OSA with a sleep test (home or in-lab) Start CPAP for immediate symptom relief and cardiovascular protection Concurrently start tirzepatide if the patient qualifies and wants weight loss After 6 to 12 months, repeat the sleep study to measure new AHI If AHI is below 5, consider weaning off CPAP under physician supervision Some patients reach normal AHI on tirzepatide alone and stop CPAP
Interaction between AMPK and PKA has been well documented in several studies 40,41,42
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