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Description
These MNs patches are mechanically strong to pierce the skin and programmed to repeatedly release semaglutide every 7 days via a single administration to maintain its plasma concentration over the course of 1 month, thus simulating the pharmacokinetic effect of multiple weekly semaglutide injections

If a small study bias was identified, we then performed the trim and fill computation to explore the effect of missing studies on the outcomes

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They had to be injected
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