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The clinical staging system of the American Joint Committee on Cancer correlates survival to size of the primary tumor (T), presence or absence of lymph node involvement (N), and presence or absence of distant metastasis (M)

Remove the vial from the refrigerator about 15-20 minutes before injection and allow it to warm to room temperature

Information last revised January 2026

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In addition, semaglutide use is not advised during pregnancy or breastfeeding, and women attempting to conceive should discontinue semaglutide medications at least two months prior to conception, as it can impact fertility.7 While there are typically no dose adjustments required for patients with renal or hepatic impairment, careful monitoring is advised for individuals who have had bariatric surgery