glp-1 cycling JCI Insight GLP-1 | Summary
Description
Weight creeps up despite genuine effort

glucagon and paracrine signaling in islet cell development
The short duration of action needed to be addressed to exploit the promising effects of GLP- 1 for the development of a clinically beneficial drug
Brain Res 782:255260

Although individual risk can be modified by genetic influences, population risk and trends in obesity over time are predominantly driven by lifestyle trends related to cultural, community, and environmental factors
