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[DOI] [PubMed] [Google Scholar] 49.Kosiborod MN, Deanfield J, Pratley R, Borlaug BA, Butler J, Davies MJ, et al

Your body is less effective at processing glucose in a state of sleep deprivation, which can lead to increased fat storage and a higher risk of weight gain

Semaglutide primarily reduces appetite and slows digestion rather than increasing your resting metabolic rate

In future RCTs, key considerations such as the optimal timing of intervention, treatment duration, specific patient subgroups based on molecular diagnosis, and potential systemic adverse events require further investigation

First, the VAT reduction was durable while treatment continued (about 18% sustained over 52 weeks, with parallel triglyceride improvement)