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For someone with type 2 diabetes, these effects can be helpful

[DOI] [PMC free article] [PubMed] [Google Scholar] 144.MacDonald PE, Salapatek AMF, Wheeler MB

Remember, though, that formulary exception requests and appeals can be time consuming

This was emphasised in the CANTOS trial, in which a monoclonal antibody targeting IL-1 in individuals with established atherosclerotic CVD and evidence of systemic inflammation reduced the risk of major adverse cardiovascular events (MACE) by 1517%, an effect that was likely to be mediated by reductions in serum CRP concentrations [80, 81]

Some might seek treatments to counteract the effects, such as boosting collagen production or maintaining skin health with professional skincare routines