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Initially studied for diabetes management and obesity, GLP-1 receptor agonists (GLP-1RAs) have garnered interest for their potential in addressing substance use disorders

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Amid rising demand, payers are grappling with whether and how to provide access to these drugs while balancing near-term costs and long-term savings potential

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4 This bidirectional activity complicates the interpretation of psychiatric outcomes in humans and may help explain the variability observed in clinical studies