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Even the GLP-1 receptor agonist class, which has actual PCOS trial data and long-standing approvals for diabetes and obesity, is used in PCOS only off-label and with explicit acknowledgment of limited evidence
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For long-term users, this raises concerns about sarcopenia, particularly in older adults
If a patient develops symptoms and findings suggestive of a lupus-like syndrome or autoimmune hepatitis following treatment with HUMIRA, discontinue treatment and evaluate the patient
