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Am J Physiol Endocrinol Metab (2001) 280:E4439
Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans
That number is a count of voluntary reports, not a rate, and it cannot prove the drugs caused those events
The nitrile forms a covalent imidate with the hydroxyl group of Ser630, which subsequently forms a hydrogen bond with the hydroxyl side group of Tyr547
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