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G.et al (2023)
doi: 10.1345/aph.1q789
Allelic variant in the glucagon-like peptide 1 receptor gene associated with greater effect of liraglutide and exenatide on gastric emptying: a pilot pharmacogenetics study
While it is still unclear as to what may cause a person taking a GLP-1 medication to experience an eye issue, researchers hypothesize that rapid changes in blood sugar levels might contribute to these eye complications
It activates G-protein coupled receptors FFAR2 and FFAR3 on L cells, triggering calcium influx and subsequent GLP-1 vesicle release
