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Lastly, they propose that tirzepatide causes a thermogenic-like amino acid profile in BAT, which could explain why obese IR mice have lower systemic BCAA levels [82]

Gut Microbes , 11(4), 855866
Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Proc Natl Acad Sci U S A (2009) 106:128590

RC: Talk with your healthcare provider before stopping the medication, as there may be more affordable options available
