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The bigger factor often appears to be the magnitude and pace of weight loss
This could potentially reduce absorption and effectiveness

The Single Most Important Fact: Mounjaros Half-Life Everything in this guide flows from one pharmacological fact: Mounjaro (tirzepatide) has a half-life of approximately five days
For others, a lower dose like 1.0 mg or 1.7 mg may be sufficient

however, no real-world studies have previously evaluated longer-term weight loss with tirzepatide in this patient population
