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This project involved contributions from numerous collaborators and trainees over several years, along with support from several institutes, including UNC School of Medicine, Keck School of Medicine of the University of Southern California, and USC Institute for Addiction Science

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Male MC4R-KO mice were fed WD for 6 weeks starting from 22 weeks of age for disease induction and were administered drugs for 7 weeks with WD feeding, for a total duration of 13 weeks