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In addition, weight loss was less pronounced in people with DM2, and long-term cardiovascular safety data in obese populations remain limited

Those interested in FDA-approved GLP-1 medications should discuss brand-name options with their provider as an alternative to compounded formulations

This level of weight loss can have substantial health benefits, including improvements in metabolic health, cardiovascular risk factors, and overall quality of life

Despite suggestions that the gastric emptying effects are greatest in the first 12 weeks and that the effect wanes weeks later, there is no certainty, and the impact on a given patient might be variable

The goal is always safety