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[PubMed ID: 28093794]

(See 6 Factors that Affect Weight Loss to learn why conventional weight-loss strategies often fail and the variables that matter most.) In that case, their metabolism has to be influenced in some way, Missimer says

In addition, a greater effect of tirzepatide on dose-dependent body weight reduction versus semaglutide was observed (least-squares mean estimated treatment difference of -1.9 kg, -3.6 kg, and -5.5 kg for the three doses

Thomsen, Dencker, et al., 2017

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