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Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All products: Signs of an allergic reaction, like rash

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When patients lose substantial weight with tirzepatideclinical trials in the SURMOUNT program have demonstrated average weight loss of 15-22% of initial body weight in people with obesity at higher dosesthe composition of that weight loss becomes clinically relevant

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If prescribed, youll receive detailed instructions from your provider on how to inject it in your stomach, arm, or thigh.