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As shown in Table 2, their main advantages are the low cost, high availability, and the high negative predictive value (NPV, i.e., a FIB-4 value 2700 patients with T2D, we showed that the agreement between these two biomarkers was low, as the proportion of patients with suspected advanced fibrosis ranged from 6.7% (FIB-4) to 33.3% (NFS) [39]

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However, based on its pharmacological profile and the cautions listed in the UK SmPCs for related approved medicines (including semaglutide and tirzepatide), certain groups are likely to require particular caution or may be excluded from future prescribing

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The EOHHS note adds that 14 states cover GLP-1s, including Massachusetts, Connecticut, and New Hampshire

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As adipose and total body mass decrease in response to the negative energy balance, less muscle mass is necessary for weight bearing, leading to atrophy

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