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Human relevance remains uncertain, but individuals with personal or family history of medullary thyroid cancer should avoid these medications as a precaution

References Aryee MJ, Jaffe AE, Corrada-Bravo H, Ladd-Acosta C, Feinberg AP, Hansen KD & Irizarry RA (2014) Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

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Some observational studies of patients with type 2 diabetes suggest that GLP-1 receptor agonist use associates with reduced dementia risk compared with other glucose-lowering medications, but these findings require cautious interpretation due to potential confounding factors

A week before the terminal experiments, echocardiograms (Vevo 3100, 15-MHz probe