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Semaglutide, the active ingredient in Wegovy, has demonstrated a 15% average body weight reduction in clinical trials when combined with lifestyle modifications

Additionally, several key clinical trial readouts delivered compelling data across multiple indications, for example (see Figure 1): Semaglutide : STEP-HFpEF (functional benefits in HFpEF), STEP-9 (pain reduction in knee osteoarthritis), STEP-10 (reversion to normoglycaemia in pre-diabetic, obese patients), ESSENCE (resolution of MASH, improvement in fibrosis) Tirzepatide : SUMMIT (risk reduction in HFpEF outcomes

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Regular check-ins with your healthcare team help detect and prevent symptomatic hypotension while maintaining cardiovascular benefits

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