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Similar content being viewed by others Introduction Amid the continuously increasing global incidence of diabetes, glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as a cornerstone in type 2 diabetes treatment, demonstrating remarkable efficacy in glycemic control and cardiovascular risk reduction [1, 2]
Other GLP-1R/GIPR co-agonists such as Cpd86 (Eli Lilly), ZP-DI-70 (Zealand) and NN9709/MAR709 (Novo Nordisk/Marcadia) have also been designed and tested in preclinical models of obesity and subsequently advanced to clinical trials (Table 1)
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Swollen lymph nodes occurring during GLP-1 therapy typically have alternative causes requiring appropriate clinical evaluation
