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Pivotal trials showed participants lost 2022% of body weight over 68 weeks

Lower insulin or sulfonylurea doses to prevent low blood sugar

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- Appetite Regulation : By acting on receptors in the brain, tirzepatide helps reduce appetite, leading to lower calorie intake and potential weight loss

Acknowledgements Medical Writing/Editorial Assistance The authors would like to acknowledge Victoria Jeter, PhD, of PRECISIONscientia in Yardley, Pennsylvania for medical writing support, as well as Ryan Ross, MS, of Merative LP in Cambridge, Massachusetts for statistical consulting support, which was funded by Novo Nordisk Inc