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Other Extra-Pancreatic Sites of GLP-1R Expression The vast range of extra-pancreatic effects exerted by GLP-1 RAs (Figure 2) may be due to the combination of multiple activated intracellular signalling pathways and the breadth of GLP-1R expression across the human body

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Beyond the Ozempic Buzz: How GLP-1s Actually Work

Other risk factors for B12 deficiency that may coexist include proton pump inhibitor or H2-antagonist use, vegan/vegetarian diets, previous bariatric surgery, pernicious anaemia, and other malabsorptive conditions

Although these findings offer reassurance regarding the safety of these drugs, further validation is essential