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One such study by McClean and colleagues [61] observed that liraglutide can cross the blood-brain barrier in substantial amounts and can prevent deficits in the water maze task performance and object recognition in AD model mice

10.1186/s12916-023-02753-6 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhou H.-R., Ma X.-F., Lin W.-J., Hao M., Yu X.-Y., Li H.-X., et al

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This peptide sequence was preceded by two basic residues which they predicted was a cleavage site that liberated it from the precursor protein