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Muscle is crucial for metabolism, strength, and long-term weight stability
Most people adjust within 12 weeks after starting semaglutide or increasing the dose
In 2014, the FDA and the EMA found no causal association between GLP-1RA and pancreatic adverse events (67)

Ileal microbial shifts after Roux-en-Y gastric bypass orchestrate changes in glucose metabolism through modulation of bile acids and L-cell adaptation
Because of rare thyroid tumours seen in animal studies, these drugs are avoided in people with a history of medullary thyroid carcinoma or MEN2