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Body Fat, Metabolic Syndrome and Hyperglycemia in South Asians

Dariush Mozaffarian 1, Monica Agarwal 2, Monica Aggarwal 3, Lydia Alexander 4, Caroline M Apovian 5, Shagun Bindlish 6, Jonathan Bonnet 7, W Scott Butsch 8, Sandra Christensen 9, Eugenia Gianos 10, Mahima Gulati 11, Alka Gupta 12 13, Debbie Horn 14, Ryan M Kane 15 16, Jasdeep Saluja 17, Deepa Sannidhi 18, Fatima Cody Stanford 19 20, Emily A Callahan 1

Broader Metabolic Health: Research indicates potential benefits for other conditions linked to metabolic dysfunction, such as non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS), by improving insulin sensitivity and reducing inflammation

however, some individuals in the retatrutide trials also showed dose-related increases in heart rate

There are several anti-obesity medications (AOMs) currently available in the USA as an adjunct to lifestyle modification, each with differing mechanisms of action (Table 1)
