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To investigate, they conducted a population-based real-world study on data from 200 million people across 21 countries within the TriNetX global network to assess whether semaglutide users possess a higher risk of NAION

The proportional odds assumption was tested with the Brant test 53

Semaglutide may also interact with certain medications, its really important to tell your healthcare provider about all the medications youre taking

This approach helps reduce side effects while still allowing for results

Variants associated with enhanced GLP-1 signaling may correlate with both stronger appetite suppression *and* heightened GI side effects, including constipation