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doi: 10.2133/dmpk.20.275

Across most of the studies the average weight loss was about 5kg

This synthesis highlights the need for continued pharmacovigilance while contextualizing the low absolute risk. This article was developed by the editorial staff in conjunction with experts in the field

Analyses of GLP-1-based trials indicate that measurable reductions in lean mass accompany total weight loss, although the relative contribution varies depending on baseline characteristics and assessment methodology [1,5,6]

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