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Compounded drugs pose a higher risk to patients than FDA-approved drugs because compounded drugs do not undergo FDA premarket review for safety, quality or effectiveness. Compounded drugs should only be used for patients whose medical needs cannot be met by an available FDA-approved drug, the agency added

The 2024 European Dermatology Forum Guidelines (51a) recommend medium-to-high dose phototherapy with UVA1 or PUVA as first-line therapy, methotrexate as second-line therapy, and other treatments including immunosuppressants, corticosteroids, intravenous immunoglobulin, and electron-beam therapy as advanced therapies (52)

By far, gastrointestinal side effects are the most common, including nausea, vomiting, and constipation

Similarly, in the combined case-control and cohort study by Wium-Andersen and colleagues, 33 low doses of metformin, DPP-4 inhibitors, GLP-1 analogs, and SGLT2 inhibitors were associated with a lower risk of depression in patients with diabetes compared to non users, with the lowest risk for sodium-glucose transport protein 2 inhibitor users

Wegovys website states: Wegovy may cause serious side effects, including: Possible thyroid tumours, including cancer