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Key Restraint/Challenge: High Initial Investment Cost of Advanced Simulators The increasing prevalence of type 2 diabetes and obesity is a major driver of the global GLP-1 Agonists market

Increasing the dose while side effects are active will amplify those effects, not resolve them

The future of therapeutic interventions for obesity may lie in developing strategies that selectively target specific GLP-1 receptor populations within the brain potentially minimising side effects while maximising their impact on appetite regulation and related behaviours such as food reward

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