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This isn't a marginal supplement category or an emerging fringe treatment - it's a class of prescription medications with a robust clinical trial data package that informed medical consensus supports for weight management in qualifying patients

[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Gibbons CH, Freeman R

We show that administration of the probiotic VSL#3 to high fat diet-fed (HFD) 3 mice reduced food intake and protected from body weight gain and insulin resistance

Most medical weight loss clinics in Honolulu do not require a referral

Similar results were achieved in a crossover study of gastric emptying after 4 weeks of treatment [62]