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In the MitoPark mouse, one of the few preclinical models of progressive PD, a clinically translatable dose of exendin-4 reduced the rate of dopaminergic neuronal loss and accompanying motor dysfunction (150), and mitigated mitochondrial dysfunction and loss (151)

Tirzepatide has received approval for use in patients with T2D following several phase 3 studies testing and demonstrating its marked anti-hyperglycemic efficacy and positive actions on multiple cardiovascular risk factors, associated with an excellent safety profile [2, 3]

Una vez que el hipotiroidismo est bien controlado, se pueden considerar medicamentos para la prdida de peso si el paciente an tiene dificultades para alcanzar un peso saludable

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