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Tirzepatide (sold as Mounjaro for T2D and Zepbound for obesity) starts at 2.5 mg and escalates in 2.5 mg increments every four weeks, up to a maximum of 15 mg

Signs Microdosing Is Not Working (Or Not Safe) People who attempt microdosing often report: No appetite changes No weight loss Unpredictable digestion Feeling worse on some days Random nausea Slower progress Needing to restart dosing again later This happens because microdosing interferes with how tirzepatide is designed to work