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In cell and animal studies, glucocorticoids reduce the gene expression that produces GLP-1 in intestinal L-cells, which is a clear and well-mapped mechanism

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Low-dose opioids may be considered in severe refractory cases under specialist supervision

These deliver more fuel per bite than high-volume, low-calorie foods like salads

Serotonin and norepinephrine reuptake inhibition and eating behavior
