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In individuals with advanced -cell dysfunction, supplementing insulin therapy with pramlintide, the first and currently only approved injectable short-acting selective analog of amylin, has demonstrated efficacy in enhancing both postprandial and overall glycemic control in both type 2 diabetes (T2D) and type 1 diabetes (T1D) without increasing the risk of hypoglycemia or weight gain

Discontinued treatment, low maintenance dosage led to reduced effectiveness of GLP-1 medications on body weight and blood sugar levels

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GLP-1 RAs, Alcohol Use disorders and Reward-Seeking Behaviors New research in JAMA Psychiatry shows that semaglutide, a GLP-1 receptor agonist, reduced alcohol consumption in adults with alcohol use disorder