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Description
Its effects are mediated by activation of GLP-1 receptors (GLP-1Rs) in the central nervous system, which help regulate hunger signals that prompt people to eat when hungry and stop when satisfied (Fig

Common examples include semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), liraglutide (Saxenda, Victoza), and dulaglutide (Trulicity)

Nauck MA, Siemsglss J, Orskov C, Holst JJ
has by far the highest rates of adults with obesity

von Scholten, B
